|Zoladex (Goserelin) is a synthetic analogue (artificial copy) of the natural female hormone Gonadotrophin Releasing Hormone (GnRH) and is a GnRH agonist (works against). Zoladex is made by AstraZeneca.
How Zoladex works
Zoladex works by blocking the production of natural Follicle Stimulating Hormone (FSH) and Leutinising Hormone (LH), which are produced by the pituitary gland at the base of the brain. Without FSH and LH the ovaries will not produce oestrogen and the body is tricked into a pseudo (false) menopause. This will reduce the growth of the deposits of endometriosis and cause them to shrink. Zoladex reduces the symptoms of endometriosis including the pain.
N.B. During the early days of treatment with Zoladex, some women experience vaginal bleeding which usually stops without any treatment.
Administration and dosage of Zoladex
When Zoladex should not be used (contra-indications)
Precautions in the use of Zoladex
Reaction of Zoladex with food/alcohol/drugs
No reactions with food, alcohol or drugs have been reported
Side effects of Zoladex
The above side effects seldom require that the treatment be stopped.
Rarely, some women enter menopause during the treatment and their periods do not restart when treatment is stopped. This could happen if a woman is nearing the natural menopause. Zoladex may cause cramps/contractions of the cervix.
As with all treatments there may be no side effects at all, or there may be a few but it is rare to experience multiple side effects. Do remember to